Mix a quarter scoop of the spoon provided with a water-based treatment in the palm of your hand and apply to the face in the morning and/or evening. Avoid contact with eyes, if contact occurs rinse thoroughly with water. Wash hands after handling. Do not mix with formulations with a pH of 5 or lower. Detailed mixing instructions available on the product website. If irritation occurs, rinse off, cease use, and consult a physician. Use only as directed on unbroken skin. Patch testing prior to use is advised. Refer to our website for a patch test guide, regimen guide, and product compatibility. Keep out of reach of children. Mixing Guide: In its truest form, Niacinamide is readily water-soluble and dissolves in water-based products, such as serums and creams, with ease. The Ordinary’s 100% Niacinamide Powder can be mixed into any non-conflicting, water-based treatment, provided that the pH of the base is between 5.0 and 7.0. When it comes to the choice of a water-based base to mix with this formula, there are several options available within The Ordinary brand. These include the following: Hyaluronic Acid 2% + B5 Natural Moisturizing Factors + HA “Buffet” + Copper Peptides 1% Matrixyl 10% + HA Argireline Solution 10% Given the powder format of the product, one may wonder how much Niacinamide is in the resulting mixture. From a theoretical standpoint, if � scoop of the powder consists approximately of 0.05g Niacinamide, then when mixed with 4 drops of the selected base, the resulting mixture is estimated to yield a 10-15% concentration of Niacinamide.